Research Articles

Organotellurium-Mediated Radical Polymerization (TERP) [PDF : 1.33 MB]

Shigeru Yamago, Professor, Institute for Chemical Research, Kyoto University

[November 2024 Release]

Selective Transformations of Aromatic Trifluoromethyl Groups [PDF : 1.08 MB]

Suguru Yoshida, Associate Professor, Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science

[August 2024 Release]

Development of typical-element-doped functional π-systems consisting of naphthalene monoimide units [PDF : 3.07 MB]

Keita Tajima,
Norihito Fukui, Associate Professor (Lecturer),
Hiroshi Shinokubo, Professor,
Department of Molecular and Macromolecular Chemistry, Graduate School of Engineering, Nagoya University

[March 2024 Release]

Inflammasome Regulation and Inflammasome Inhibitors [PDF : 649 KB]

Junya Masumoto, Professor,
Naoe Kaneko,
Department of Pathology, Ehime University Proteo-Science Center and Graduate School of Medicine

[November 2023 Release]

Pyrrole-Imidazole Polyamide – A Front Runner in Mid-Molecular Pharmaceuticals [PDF : 7.72 MB]

Thangavel Vaijayanthi,
Ganesh N. Pandian, Associate Professor,
Hiroshi Sugiyama, Professor,
Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University

[August 2023 Release]

One-pot γ-Lactonization of Homopropargyl Alcohol via Intramolecular Ketene Trapping – Its discovery, optimization, and application – [PDF : 0.99 MB]

Masaki Ohtawa, Associate Professor, School of Pharmacy, Kitasato University

[March 2023 Release]

Protecting Group-Free Glycosylations [PDF : 1.51 MB]

Shin-ichiro Shoda, Professor Emeritus, Tohoku University

[December 2022 Release]

Development and Applications of Plant Tissue-Clearing Technology [PDF : 872 KB]

Yuki Sakamoto, Assistant Professor, Department of Biological Sciences, Graduate School of Science, Osaka University

[August 2022 Release]

Characteristic Reactivity of an All-Carbon-Substituted Diborane(4), B₂(o-tol)₄ [PDF : 1.11 MB]

Makoto Yamashita, Professor, Graduate School of Engineering, Nagoya University

[March 2022 Release]

Basics and Applications of Tissue Clearing Technology [PDF : 1.08 MB]

Etsuo A. Susaki, Professor,
Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine Laboratory for Synthetic Biology
RIKEN Center for Biosystems Dynamics Research

[March 2022 Release]

Nucleic Acid Delivery System with DOP-DEDA, a Charge-Reversible Lipid Derivative [PDF : 644 KB]

Tomohiro Asai, Professor, University of Shizuoka, School of Pharmaceutical Sciences

[August 2021 Release]

Preparing Liposome Mixtures with Nippon Fine Chemical's High-purity Phospholipids and Presomes^® Series [PDF : 758 KB]

Koji Tomita,
Noriyuki Maeda,
Masaki Matsumoto,
Fine Chemical Division, Lipid Department, NIPPON FINE CHEMICAL CO., LTD.

[August 2021 Release]

Trifluoromethanesulfonic Anhydride in Amide Activation: A Powerful Tool to Forge Heterocyclic Cores [PDF : 0.98MB]

Haoqi Zhang,
Margaux Riomet,
Nuno Maulide, Professor,
Institute of Organic Chemistry, University of Vienna

[April 2021 Release]

Sequential Triple Cross-Coupling towards Synthesis of 2,4,5-Trisarylthiazoles [PDF : 827KB]

Michael Schnürch, Associate Professor, Institute of Applied Synthetic Chemistry, TU Wien

[December 2020 Release]

Current Status of Drug development against the Novel Coronavirus, SARS-CoV-2 ―Evaluation of therapeutic agents based on scientific evidence― [PDF : 1.2MB]

Makoto Ujike, Associate Professor, Faculty of Veterinary Science, Nippon Veterinary and Life Science University

[August 2020 Release]

Design of Bifunctional Tetraarylphosphonium Salt Catalysts [PDF : 516KB]

Yasunori Toda, Assistant Professor,
Hiroyuki Suga, Professor,
Department of Materials Chemistry, Faculty of Engineering, Shinshu University

[April 2020 Release]

Designer C₂-symmetric Chiral Diamide-type Organoiodine Catalysts [PDF : 1.8MB]

Muhammet Uyanik, Assistant Professor,
Kazuaki Ishihara, Professor,
Graduate School of Engineering, Nagoya University

[December 2019 Release]

Poly(2-oxazoline)s: The Versatile Polymer Platform [PDF : 1.9MB]

Victor R. de la Rosa, Avroxa BV
Richard Hoogenboom, Professor, Faculty of Science, Ghent University

[August 2019 Release]

Anilido PNP Pincer and Relevant Complexes [PDF : 825KB]

Lan-Chang Liang, Distinguished Professor,
Department of Chemistry, National Sun Yat-sen University, Taiwan
Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Taiwan

[April 2019 Release]

Asymmetric Synthesis of Axially Chiral Compounds by Rhodium(I)-Catalyzed [2+2+2] Cycloaddition [PDF:585KB]

Ken Tanaka, Professor, Department of Chemical Science and Engineering, Tokyo Institute of Technology

[November 2018 Release]

Carbocyclization of Carbohydrates to Hydroxylated Cycloalka(e)nes [PDF:1.5MB]

Tony K. M. Shing, Professor, Department of Chemistry, Faculty of Science and Technology, Keio University

[July 2018 Release]

DABCO-bis(sulfur dioxide), DABSO, as a Source of Sulfur Dioxide in Transition Metal-Catalyzed Reactions [PDF:933KB]

Michael C. Willis, Professor, Department of Chemistry, University of Oxford, Chemistry Research Laboratory

[January 2018 Release]

Silver-Catalyzed CO2 Incorporation Reactions [PDF:1.0MB]

Tohru Yamada, Professor, Department of Chemistry, Keio Univeristy

[October 2017 Release]

Development of P-Chirogenic Phosphine Ligands Based on Chemistry of Phosphine-Boranes: Searching for Novelty and Utility in Synthetic Organic Chemistry [PDF:1.2MB]

Tsuneo Imamoto, Professor Emeritus, Chiba University

[July 2017 Release]

Development of an Air-Stable Precatalyst for Use in Homogeneous Nickel Catalysis: A Case Study in the Mizoroki-Heck Reaction of Benzyl Chlorides and Simple Alkenes [PDF:450KB]

Eric A. Standley, Research Scientist, Gilead Sciences, Inc.
Timothy F. Jamison, Professor, Department of Chemistry, Massachusetts Institute of Technology

[July 2017 Release]

Science “Special” Seminar: New Ruthenium(II) Thiolate Complexes: Cooperative Activation of E-H Bonds (E = H, Si, B) and Catalytic Applications [PDF:538KB]

Martin Oestreich, Professor, Institut für Chemie, Technische Universität Berlin

[July 2017 Release]

Aryl(2,4,6-trimethoxyphenyl)iodonium Salts as Reagents for Metal-Free Arylation of Carbon and Heteroatom Nucleophiles [PDF:573KB]

David R. Stuart, Assistant Professor, Department of Chemistry, Portland State University, United States

[April 2017 Release]

Asymmetric Catalysis with Chiral Bis(oxazolinyl)phenyl Transition-metal Complexes [PDF:935KB]

Hisao Nishiyama, Emeritus Professor, Nagoya University

[January 2017 Release]

Development of Novel Methodologies in Organic Synthesis Based on Ate Complex Formation [PDF:1.9MB]

Keiichi Hirano, Assistant Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Masanobu Uchiyama, Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo Chief Scientist (Joint Appointment), RIKEN

[October 2016 Release]

Furan Photo-oxidation Based Click Reactions: Labeling, Crosslinking and Conjugation of Peptides and Oligonucleotides under Physiological Conditions [PDF:527KB]

Annemieke Madder, Professor, Department of Organic and Macromolecular Chemistry, Ghent University, Belgium

[October 2016 Release]

Development of Novel P-chiral Phosphorus Ligands for Efficient Transition-Metal Catalyzed Reactions [PDF:1.0MB]

Guangqing Xu, Assistant Researcher,
Wenjun Tang, Professor,
State Key Laboratory of Bio-Organic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

[July 2016 Release]

A New Air-stable Fluorinating Reagent, IF₅-pyridine-HF [PDF:574KB]

Shoji Hara, Specially Appointed Professor, Graduate School of Engineering, Hokkaido University

[April 2016 Release]

Chemistry―A Structurally Based Science: My Journey from the Beauty in Fullerene Chemistry to Supramolecular Material Chemistry [PDF:763KB]

Hsiu-Fu Hsu, Professor, Department of Chemistry, Tamkang University, Taiwan

[January 2016 Release]

Invention of Synthetic Reactions Based on σ-Bond Activation [PDF:785KB]

Tamejiro Hiyama, RDI Professor, Research and Development Initiative, Chuo University

[July 2015 Release]

New Synthetic Pathways to Well-Defined Oligothiophenes and Polythiophenes via C-H Coupling Reactions [PDF:1.1MB]

Shunsuke Tamba,
Shota Tanaka,
Atsunori Mori, Professor,
Graduate School of Engineering, Kobe University

[December 2014 Release]

Exploration and Design of Novel Asymmetric Catalysts: Development of Imidazoline-aminophenol (IAP) and Bis(imidazolidine)pyridine (PyBidine) [PDF:1.3MB]

Takayoshi Arai, Professor, Department of Chemistry, Graduate School of Science, Chiba University

[November 2014 Release]

Air-Stable Emissive Disilenes Protected by Fused-Ring Bulky “Rind” Groups [PDF:435KB]

Tsukasa Matsuo, Associate Professor, Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University

[October 2014 Release]

Innovative Molecular Design of Chiral 1,1′-Binaphthyl 2,2′-Disulfonic Acid (BINSA) [PDF:1.4MB]

Manabu Hatano, Associate Professor,
Keisuke Nishikawa, Postdoctoral fellow,
Kazuaki Ishihara, Professor,
Graduate School of Engineering, Nagoya University

[January 2014 Release]

Polymerizable ionic liquids: Development to photo functional poly(ionic liquid) materials [PDF:766KB]

Jun-ichi Kadokawa, Professor, Graduate School of Science and Engineering, Kagoshima University

[October 2013 Release]

The High Functionality of Glycosylation Using Plant Suspension Cells [PDF:612KB]

Hiroki Hamada, Professor, Department of Life Science, Faculty of Science, Okayama University of Science
Kei Shimoda, Associate Professor, Department of Chemistry, Faculty of Medicine, Oita University

[August 2013 Release]

Science “Summer” Seminar: Carbonyl Olefination (3) [PDF:517KB]

Takeshi Takeda, Professor, Department of Applied Chemistry, Tokyo University of Agriculture and Technology

[July 2013 Release]

Science “Special” Seminar: Can Resveratrol be the Multidrug in Longevity Society? [PDF:342KB]

Yoko Fujiwara, Professor, Graduate School of Humanities and Sciences, Ochanomizu University

[July 2013 Release]

Study of Ion-supported Reagents for Organic Synthesis: IS-Ph₃P, IS-MSO, IS-MS, and IS-DIB [PDF:930KB]

Hideo Togo, Professor, Graduate School of Science, Chiba University

[April 2013 Release]

Science “Spring” Seminar: Carbonyl Olefination (2) [PDF:570KB]

Takeshi Takeda, Professor, Department of Applied Chemistry, Tokyo University of Agriculture and Technology

[April 2013 Release]

Science “Winter” Seminar: Carbonyl Olefination (1) [PDF:607KB]

Takeshi Takeda, Professor, Department of Applied Chemistry, Tokyo University of Agriculture and Technology

[January 2013 Release]

Syntheses of Catechol Diterpenes and Their Biological Activities [PDF:802KB]

Masahiro Tada,

Professor Emeritus, Tokyo University of Agriculture and Technology

[December 2012 Release]

N-Mesityl Substituted Chiral Triazolium Salts: Opening a New World of N-Heterocyclic Carbene Catalysis [PDF:998KB]

Pei-Chen Chiang, Graduate student, Department of Chemistry, University of Pennsylvania
Jeffrey W. Bode, Professor, Laboratorium für Organische Chemie, ETH-Zürich

[December 2012 Release]

A Synthetic Biology Approach to the Expansion of the Genetic Alphabet: Molecular Design of Unnatural Base Pairs of DNA [PDF:1.3MB]

Ichiro Hirao, Team Leader,
Michiko Kimoto, Researcher,
Nucleic Acid Synthetic Biology Research Team, RIKEN SSBC

[August 2012 Release]

Bifunctional Molecular Catalysts with Cooperating Amine/Amido Ligands [PDF:571KB]

Yoshihito Kayaki, Assistant Professor,
Takao Ikariya, Professor,
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology

[August 2012 Release]

Recent Researches on Construction of Artificial Helical Polymers Practical Molecular Design Methodology by the Factors for Inducing and Maintaining Helical Structures on the Basis of Classification of Main Chain Skeleton [PDF:2.5MB]

Akiko Okamoto, Assistant Professor,
Hideaki Oike, Assistant Professor,
Noriyuki Yonezawa, Professor,
Department of Organic and Polymer Materials Chemistry, Tokyo University of Agriculture and Technology

[March 2012 Release]

Oxoammonium Salt Oxidations of Alcohols [PDF:1.5MB]

James M. Bobbitt, Professor, Chemistry Emeritus, University of Connecticut

[August 2011 Release]

Various Synthetic Methods Using Aromatic Carboxylic Anhydrides [PDF:2.5MB]

Isamu Shiina, Professor, Faculty of Science, Tokyo University of Science

[March 2011 Release]

Control of Superstructures of Liquid-Crystalline Molecules Using Lateral Intermolecular Interactions [PDF:1.9MB]

Keiki Kishikawa, Professor, Graduate School of Engineering, Chiba University

[August 2010 Release]

Structural Characteristic of Iron(III) Chelates to Induce Tissue Damage and Renal Carcinoma; Chemical Origin of the Iron Toxicity [PDF:2.9MB]

Yuzo Nishida, Professor, Yamagata University

[May 2010 Release]

Development of Novel Catalytic Asymmetric Reactions using Cationic Group-10 Metal Complexes: With a Special Focus on Reactions in which Palladium Enolate Plays a Key Role [PDF:3.0MB]

Yoshitaka Hamashima, Senior Research Scientist, Synthetic Organic Chemistry Laboratory, RIKEN
Mikiko Sodeoka, Chief Scientist, Synthetic Organic Chemistry Laboratory, RIKEN

[March 2010 Release]

Development of Highly Potent Chiral Discrimination Methods that Solve the Problems of Diastereomer Method [PDF:3.5MB]

Hiroshi Ohrui, Professor, Yokohama College of Pharmacy

[January 2010 Release]

Environmental-friendly Catalysts Learned from Vitamin B₁₂-Dependent Enzymes [PDF:829KB]

Hisashi Shimakoshi, Assistant Professor, Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University
Yoshio Hisaeda, Professor, Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University

[August 2009 Release]

Chemistry of Trifluoroacetimidoyl Halides as Versatile Fluorine-containing Building Bloks [PDF:200KB]

Kenji Uneyama, Professor of Emeritus, Department of Applied Chemistry, Okayama University

[March 2009 Release]

Photocontrol of the Coordination Numbers of the Main Group Elements: Properties of Azobenzenes Bearing a Main-Group-Element Substituent and Their Application [PDF:159KB]

Naokazu Kano, Associate Professor, Department of Chemistry, Graduate School of Science, The University of Tokyo
Takayuki Kawashima, Professor, Department of Chemistry, Graduate School of Science, The University of Tokyo

[December 2008 Release]

Structural Change of Dimeric SOD Enzyme and Amyotrophic Lateral Sclerosis (ALS) [PDF:120KB]

Yuzo Nishida, Professor, Yamagata University

[July 2008 Release]

A reliable and easy method for synthesis of nitrogen-containing compounds: Ns-strategy and with high-activity trityl type resin [PDF:354KB]

Toshiyuki Kan, Professor, Laboratory of Synthetic and Medical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka
Tohru Fukuyama, Professor, Laboratory of Synthetic Natural Products Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo

[March 2008 Release]

Diphenyl Phosphorazidate (DPPA) ― More Than Three Decades Later [PDF:433KB]

Takayuki Shioiri, Professor, Graduate School of Environmental and Human Sciences, Meijo University

[October 2007 Release]

A Novel Method for the formation of C-N Bonds Using Oxime Derivatives [PDF:314KB]

Mitsuru Kitamura, Specified Assistant Professor,
Koichi Narasaka, Professor,
Department of Chemistry, Graduate School of Science, The University of Tokyo

[August 2007 Release]

Synthesis of Bioactive Glycoconjugates Using the Transglycosylation Activity of Microbial Endoglycosidase [PDF:91KB]

Kenji Yamamoto, Professor, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University

[March 2007 Release]

Fascination of metallosalen complexes: Diverse catalytic performances and high asymmetry-inducing ability [PDF:319KB]

Tsutomu Katsuki, Professor, Department of Chemistry, Faculty of Science, Graduate School, Kyushu University

[April 2006 Release]

New Mitsunobu Reagents [PDF:352KB]

Tetsuto Tsunoda, Professor,
Hiroto Kaku, Research Associate,
Shô Itô, Professor Emeritus,
Tokushima Bunri University, Pharmaceutical Sciences

[July 2005 Release]

Thiacalixarenes: the development of new host molecules utilizing the characteristics of sulfur [PDF:366KB]

Naoya Morohashi, Research Associate, Faculty of Engineering, Yamagata University
Sotaro Miyano, Director, Fukushima Technology Centre

[February 2005 Release]

Development of New Iodocyclization and Radical Cycloaddition Reaction [PDF:237KB]

Osamu Kitagawa, Lecturer,
Takeo Taguchi, Professor,
Laboratory of Synthetic Organic Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science

[August 2004 Release]

The use of Diarylethene Derivatives for Photo-switching [PDF:621KB]

Kenji Matsuda, Research Associate,
Masahiro Irie, Professor,
Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University

[June 2004 Release]

Application of Saccharides to the Synthesis of Biologically Active Compounds [PDF:551KB]

Shiro Ikegami, Professor,
Hideyo Takahashi, Associate Professor,
Laboratory of Synthetic Organic and Medicinal Chemistry School of Pharmaceutical Sciences, Teikyo University

[March 2004 Release]

Molecular Capsules : Container Compounds with an Isolated Nanoscale Cavity [PDF:391KB]

Masatsugu Ayabe, Ph.D., Department of Biochemistry and Chemistry Graduate School of Engineering, Kyushu University
Seiji Shinkai, Professor, Department of Applied Chemistry Graduate School of Engineering, Kyushu University

[January 2004 Release]

Powerful Novel Chiral Acids for Enantioresolution, Determination of Absolute Configuration, and MS Spectral Determination of Enantiomeric Excess [PDF:591KB]

Nobuyuki Harada, Professor, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University

[October 2003 Release]

Discovery of a carbon radical producing catalyst and its application to organic synthesis [PDF:384KB]

Yasutaka Ishii, Professor,

Satoshi Sakaguchi, Assistant,
Faculty of Engineering, KU-HRC, Kansai University

[April 2003 Release]

The development of new chemistry on multiple-bond compounds with heavier main group elements [PDF:152KB]

Renji Okazaki, Professor, Faculty of Science, Japan Women's University

[June 2001 Release]

Utilization of Iodine Resources [PDF:143KB]

Masahito Ochiai, Professor, Faculty of Pharmaceutical Sciences, University of Tokushima

[October 1999 Release]

1,1-Dimethyleneallyl Palladium Complexes : Preparation and Synthetic Potential [PDF:189KB]

Jacques SALAUN, Professor, Universite de Paris-Sud

[July 1999 Release]

From Asymmetric Catalyst to Asymmetric Autocatalyst [PDF:142KB]

Kenso Soai, Professor,
Takanori Shibata, Research Associate,
Department of Applied Chemistry, Science University of Tokyo

[April 1999 Release]