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CAS RN: 146939-27-7 | Product Number: Z0034
Ziprasidone
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 100MG |
¥360.00
|
3 | 6 | 3 |
| 1G |
¥2,550.00
|
Contact Us | 1 | 1 |
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| Product Number | Z0034 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__1ClN__4OS = 412.94 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 146939-27-7 |
| Reaxys Registry Number | 6669199 |
| PubChem Substance ID | 253660462 |
| Merck Index (14) | 10171 |
| MDL Number | MFCD00866661 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Melting point | 218.0 to 224.0 °C |
Properties (reference)
| Melting Point | 222 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 2.1 mg/l 25 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H336 : May cause drowsiness or dizziness. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P271 : Use only outdoors or in a well-ventilated area. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| RTECS# | NM3241000 |
Transport Information:
| Customs Control Conditions (Q) |
Application
Ziprasidone: A Unique Combined 5-HT and Dopamine Receptor Antagonist
Ziprasidone is a combined 5-HT (serotonin, [S0370 (Hydrochloride)]) and dopamine [A0305 (Hydrochloride)] receptor antagonist. The mechanism of action of ziprasidone, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been reported that has high affinity for serotonin 5-HT2A and dopamine D2 receptors in vitro.
References
- Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity
- 5-HT1A receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex
- Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile
- Ziprasidone: the fifth atypical antipsychotic (a review)
- Ziprasidone Metabolism, Aldehyde Oxidase, and Clinical Implications
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Articles/Brochures
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