Maximum quantity allowed is 999
Please select the quantity
CAS RN: 322-79-2 | Product Number: T3601
Triflusal
×
![]()
×
Purity: >98.0%(T)
Synonyms:
- Acetyl-4-(trifluoromethyl)salicylic Acid
- 2-Acetoxy-4-(trifluoromethyl)benzoic Acid
- Drisgen
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 250MG |
¥440.00
|
1 | Contact Us | 1 |
| 1G |
¥1,200.00
|
Contact Us | Contact Us | 6 |
* For order or inquiry, please contact
Our Authorized Distributors.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
| Product Number | T3601 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__0H__7F__3O__4 = 248.16 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 322-79-2 |
| Reaxys Registry Number | 2945374 |
| PubChem Substance ID | 354335089 |
| Merck Index (14) | 9688 |
| MDL Number | MFCD00866793 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 96.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 113.0 to 117.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 115 °C |
| Maximum Absorption Wavelength | 297(H2O) nm |
| Solubility in water | Insoluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
Transport Information:
| Customs Control Conditions (Q) |
Application
Triflusal: An Antiplatelet Aggregation Agent
Triflusal is an antiplatelet aggregation agent having a trifluoromethyl group at the 4-position. It is metabolized to 2-hydroxy-4-trifluoromethylbenzoic acid (HTB) which inhibits cyclogxygenase-1 (COX-1) in platelets. Furthermore, both triflusal and HTB are also able to increase cyclic adenosine monophosphate (cAMP) [A2381] levels in platelets through inhibition of platelet phosphodiesterases which regulate intracellular cAMP levels. Moreover, triflusal enhances the production of NO by neutrophils via stimulation of the constitutive activity of nitric oxide (NO) synthase (cNOS). It is considered that triflusal shows the antiplatelet aggregation activity by these actions. (The product is for research purpose only.)
References
- Triflusal: An Old Drug in Modern Antiplatelet Therapy. Review of Its Action, Use, Safety and Effectiveness
- Determination of triflusal in human plasma by high performance liquid chromatography with automated column switching system
- Simultaneous determination of triflusal and its major active metabolite, 2-hydroxy-4-trifluoromethyl benzoic acid, in rat and human plasma by high-performance liquid chromatography
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.