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CAS RN: 49763-96-4 | Product Number: S0905
Stiripentol
![Stiripentol No-Image](/medias/S0905.jpg?context=bWFzdGVyfHJvb3R8NDEyNTZ8aW1hZ2UvanBlZ3xhREJtTDJnellTODRPVEl6TVRrM056TTBPVFF5TDFNd09UQTFMbXB3Wnd8NDVmZWZhNGRjMzQwOTBjNWFhNDEzODVkNzIzMjg1YzJiYjM1M2NkY2E0N2NjNTQ4ODE4OWQzOTM3YjY1OTc0ZQ)
Purity: >98.0%(GC)
Synonyms:
- 4,4-Dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-ol
- 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol
Product Documents:
Size | Unit Price | Shanghai | Tianjin | Japan* |
---|---|---|---|---|
1G |
¥240.00
|
≥40 | 1 | 1 |
5G |
¥950.00
|
Contact Us | Contact Us | 28 |
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Product Number | S0905 |
Purity / Analysis Method | >98.0%(GC) |
Molecular Formula / Molecular Weight | C__1__4H__1__8O__3 = 234.30 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 49763-96-4 |
Reaxys Registry Number | 1313047 |
PubChem Substance ID | 253660381 |
MDL Number | MFCD00869310 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 75.0 to 79.0 °C |
Properties (reference)
Melting Point | 77 °C |
GHS
Related Laws:
RTECS# | SB3393000 |
Transport Information:
Customs Control Conditions (Q) |
Application
Stiripentol (STP): A Third Generation Antiepileptic Agent with Multiple Mechanisms of Action
Stiripentol (STP), a third generation antiepileptic agent, has multiple mechanisms of action. STP has recently been proved to increase the GABAergic transmission in animal experimental models. STP also acts as a potent inhibitor of CYP3A4, CYP1A2 and CYP2C19 and increases the plasma concentrations of many other antiepileptic agents. (The product is for research purpose only.)
References
- Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: in vitro and in vivo comparison and calculation of in vivo inhibition constants
- Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABAA-receptor channels
- In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism
- The anticonvulsant stiripentol acts directly on the GABAA receptor as a positive allosteric modulator
- Stiripentol (a review)
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