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CAS RN: 69617-84-1 | Product Number: R0121
Rhododendrol
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Purity: >98.0%(GC)
Synonyms:
- 4-(4-Hydroxyphenyl)-2-butanol
- 4-(3-Hydroxybutyl)phenol
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 1G |
¥390.00
|
20 | 1 | 31 |
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| Product Number | R0121 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4O__2 = 166.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 69617-84-1 |
| Reaxys Registry Number | 2437673 |
| PubChem Substance ID | 253661975 |
| MDL Number | MFCD01117650 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 68.0 to 72.0 °C |
Properties (reference)
| Melting Point | 70 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Transport Information:
| Customs Control Conditions (Q) |
Application
Rhododendrol: An Inhibitor of Tyrosinase.
Rhododendrol (chemical name) is a phenol compound found in extracts of White Birch (Betula pubescens) and Nikko Maple (Acer nikoense). Rhododendrol suppresses melanin biosynthesis and the mechanism is shown to be due to its competitive inhibition of tyrosinase activity. However, rhododendrol have also been found to cause white blotches on skin. Although its mechanism of action remains unknown exactly, there is a report that the white blotches may be caused by metabolites of rhododendrol.
References
- Rhododendrol biosynthesis and metabolism in Acer nikoense callus
- Quasi-Drugs Developed in Japan for the Prevention or Treatment of Hyperpigmentary Disorders
- Melanogenesis-Inhibitory and Cytotoxic Activities of Diarylheptanoids from Acer nikoense Bark and Their Derivatives
- Rhododendrol, a depigmentation-inducing phenolic compound, exerts melanocyte cytotoxicity via a tyrosinase-dependent mechanism
- Biochemical, cytological, and immunological mechanisms of rhododendrol-induced leukoderma
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