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CAS RN: 19237-84-4 | Product Number: P0938
Prazosin Hydrochloride
Purity: >98.0%(T)
Synonyms:
- 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine Hydrochloride
Product Documents:
Size | Unit Price | Shanghai | Tianjin | Japan* |
---|---|---|---|---|
100MG |
¥340.00
|
3 | 12 | 18 |
1G |
¥1,580.00
|
2 | 1 | 14 |
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Product Number | P0938 |
Purity / Analysis Method | >98.0%(T) |
Molecular Formula / Molecular Weight | C__1__9H__2__1N__5O__4·HCl = 419.87 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Condition to Avoid | Light Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 19237-84-4 |
Related CAS RN | 19216-56-9 |
Reaxys Registry Number | 4303561 |
PubChem Substance ID | 87575055 |
Merck Index (14) | 7717 |
MDL Number | MFCD00058177 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(Argentometric Titration) | min. 98.0 % |
Properties (reference)
Melting Point | 285 °C |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
RTECS# | VA1350000 |
Transport Information:
Customs Control Conditions (Q) |
Application
Prazosin Hydrochloride: A Highly Selective α1-Adrenoceptor Antagonist
Prazosin hydrochloride, a highly lipophilic quinazoline derivative, is a highly selective α1-adrenoceptor antagonist. Prazosin causes a decrease in total peripheral resistance and a decrease in the contractions in smooth muscle of prostatic capsule. Animal studies have suggested that the effects of prazosin are related to blockade of α1-adrenoceptors. Prazosin hydrochloride is used to treat hypertension and benign prostatic hyperplasia in clinical use. (The product is for research purpose only.)
References
- Prazosin, a selective antagonist of post-synaptic α-adrenoceptors
- Prazosin update. A review of its pharmacological properties and therapeutic use in hypertension and congestive heart failure
- The use of α-adrenoceptor antagonists in the pharmacological management of benign prostatic hypertrophy: An overview
- Prazosin hydrochloride (a review discussing the physical properties, preparation, solubility, polymorphism, metabolism and pharmacokinetics, and detction of prazosin)
- A review on various analytical methods on some alpha adrenergic antagonists
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