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CAS RN: 3282-30-2 | Product Number: P0677

Pivaloyl Chloride


Purity: >98.0%(T)
Synonyms:
  • 2,2-Dimethylpropionyl Chloride
  • Trimethylacetyl Chloride
Product Documents:
25ML
¥220.00
11   Contact Us ≥40 
500ML
¥550.00
3   Contact Us ≥80 

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Product Number P0677
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__5H__9ClO = 120.58 
Physical State (20 deg.C) Liquid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Moisture Sensitive,Heat Sensitive
CAS RN 3282-30-2
Reaxys Registry Number 385668
PubChem Substance ID 125310048
SDBS (AIST Spectral DB) 2154
MDL Number

MFCD00000709

Specifications
Appearance Colorless to Light yellow clear liquid
Purity(Argentometric Titration) min. 98.0 %
Properties (reference)
Boiling Point 106 °C
Flash point 13 °C
Specific Gravity (20/20) 0.99
Refractive Index 1.41
Solubility (soluble in) Ether, Acetone
GHS
Pictogram Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H330 : Fatal if inhaled.
H302 : Harmful if swallowed.
H313 : May be harmful in contact with skin.
H314 : Causes severe skin burns and eye damage.
H370 : Causes damage to organs.
H402 : Harmful to aquatic life.
H225 : Highly flammable liquid and vapor.
H290 : May be corrosive to metals.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P240 : Ground/bond container and receiving equipment.
P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P233 : Keep container tightly closed.
P234 : Keep only in original container.
P243 : Take precautionary measures against static discharge.
P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment.
P242 : Use only non-sparking tools.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 : Wear respiratory protection.
P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P390 : Absorb spillage to prevent material damage.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 : Wash contaminated clothing before reuse.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P403 + P235 : Store in a well-ventilated place. Keep cool.
P406 : Store in corrosive resistant container with a resistant inner liner.
P405 : Store locked up.
Related Laws:
CN Number 1815
Transport Information:
UN Number UN2438
Class 6.1 / 3,8
Packing Group I
Customs Control Conditions (Q)
Application
Mild Chlorination of Alcohols

Typical Procedure (Chlorination of p-methoxybenzyl alcohol): A mixture of pivaloyl chloride (1.30 g, 10.86 mmol) and DMF (5 mL) is stirred at room temperature for 1 h. To the mixture is first added CH2Cl2 (25 mL) followed by alcohol (1 g, 7.24 mmol). The reaction is monitored (TLC) until the complete disappearance of starting material. Water (20 mL) is added, and then the organic phase is washed with 15 mL of a saturated solution of Na2CO3, followed by 1 N HCl and brine. The organic layers are dried over Na2SO4, and the solvent evaporated to yield p-methoxybenzyl chloride (0.91 g, 80%).

References


PubMed Literature


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