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CAS RN: 751-03-1 | Product Number: O0506
Obacunone
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Purity: >98.0%(HPLC)
Synonyms:
- Obacunoic Acid ε-Lactone
- Obacunoic Acid 3,4-Lactone
- (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(Furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 100MG |
¥1,330.00
|
3 | Contact Us | 24 |
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| Product Number | O0506 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__3__0O__7 = 454.52 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 751-03-1 |
| Related CAS RN | 6483-15-4 |
| Reaxys Registry Number | 68347 |
| MDL Number | MFCD00075888 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 227.0 to 231.0 °C |
| Specific rotation | -49.0 to -53.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 229 °C |
GHS
Related Laws:
| RTECS# | RR1104200 |
Transport Information:
| Customs Control Conditions (Q) |
Application
Obacunone: A Type of Limonoid with Various Pharmacological Activities Such As Anticancer and Anti-Inflammatory
Limonoids are a class of oxygenated terpenoids found primarily in citrus fruits. Obacunone is a type of limonoid with various pharmacological activities such as anticancer, antioxidant, anti-inflammatory, antidiabetic, neuroprotective, antibiosis, and antiviral. Among them, the anticancer effect is the most prominent. (The product is for research purpose only.)
References
- The pharmacological and pharmacokinetic properties of obacunone from citrus fruits: A comprehensive narrative review
- Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis
- Obacunone causes sustained expression of MKP-1 thus inactivating p38 MAPK to suppress pro-inflammatory mediators through intracellular MIF
- Simultaneous determination of limonin, dictamnine, obacunone and fraxinellone in rat plasma by a validated UHPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Cortex Dictamni extract
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