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CAS RN: 484-12-8 | Product Number: O0426
Osthole
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Purity: >98.0%(GC)
Synonyms:
- 7-Methoxy-8-(3-methyl-2-butenyl)coumarin
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 250MG |
¥160.00
|
2 | 1 | 16 |
| 1G |
¥490.00
|
1 | 1 | 4 |
| 5G |
¥1,990.00
|
Contact Us | Contact Us | 12 |
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| Product Number | O0426 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__6O__3 = 244.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 484-12-8 |
| Reaxys Registry Number | 1288399 |
| PubChem Substance ID | 253662100 |
| Merck Index (14) | 6895 |
| MDL Number | MFCD00076049 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 82.0 to 86.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 84 °C |
| Maximum Absorption Wavelength | 322 nm (MeOH) |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Ethanol |
GHS
| Signal Word | Warning |
| Hazard Statements | H303 : May be harmful if swallowed. |
| Precautionary Statements | P312 : Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
| RTECS# | GN7700000 |
Transport Information:
| Customs Control Conditions (Q) |
Application
Efflux pump inhibitor
References
- Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: Reversing the resistance against frontline antibacterial drugs
Application
A Crude Drug Ingredient in Cnidii Monnieri Fructus and etc.
Osthol is a natural coumarin that found in a variety of plants including Cnidium monnieri, Angelica archangelica and Angelica pubescens. Osthol is an ingredient of a Traditional Chinese Medicine (TCM), and has received attention recently because of its significant and diverse pharmacological activities, including anticancer, anti-osteoporotic, and anti-proliferative activities. (The product is for research purpose only.)
References
- Osthole-mediated cell differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway in human osteoblast cells
- Anti-allergic effects of Cnidii Monnieri Fructus (dried fruits of Cnidium monnieri) and Iits major component, osthol
- Coumarins from Cnidium monnieri and their antiosteoporotic activity
- Antitumor effects of Osthol from Cnidium monnieri: an in vitro and in vivo study
- Osthole: a promising lead compound for drug discovery from a Traditional Chinese Medicine (TCM) (a review)
- Potential Anticancer Properties of Osthol: A Comprehensive Mechanistic Review
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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