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CAS RN: 78712-43-3 | Product Number: O0419

Ozagrel Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic Acid Hydrochloride
  • trans-4-[(1-Imidazolyl)methyl]cinnamic Acid Hydrochloride
Product Documents:
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Supplemental Product Information:

Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.

Product Number O0419
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__3H__1__2N__2O__2·HCl = 264.71 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 78712-43-3
Related CAS RN 82571-53-7&189224-26-8
Reaxys Registry Number 5173590
PubChem Substance ID 253659529
Merck Index (14) 6980
MDL Number

MFCD06795644

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %(calcd.on anh.substance)
Water 5.0 to 8.0 %
Properties (reference)
Melting Point 217 °C
Solubility in water Soluble
Degree of solubility in water 181 g/l   37 °C
Solubility (slightly sol. in) Ethanol
Solubility (insoluble in) Ether
GHS
Signal Word Warning
Hazard Statements H303 : May be harmful if swallowed.
Precautionary Statements P312 : Call a POISON CENTER/doctor if you feel unwell.
Related Laws:
RTECS# UD3380000
Transport Information:
Customs Control Conditions (Q)
Application
強力かつ選択的なトロンボキサンA2合成酵素 (TXA2合成酵素) 阻害剤,オザグレル

Thromboxane A2 (TXA2) is an important metabolite of arachidonic acid cascade involved in a variety of cellular functions and diseases. TXA2 synthase activity is selectively inhibited by Ozagrel.

References


PubMed Literature


TCIMAIL
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