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CAS RN: 82956-11-4 | Product Number: N0959

Nafamostat Mesylate


Purity: >98.0%(HPLC)
Synonyms:
  • 6-Amidino-2-naphthyl 4-Guanidinobenzoate Bis(methanesulfonate)
  • 4-Guanidinobenzoic Acid 6-Amidino-2-naphthyl Ester Bis(methanesulfonate)
Product Documents:
20MG
¥290.00
2   1   ≥100 
100MG
¥730.00
1   1   ≥100 

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Supplemental Product Information:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number N0959
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__1__7N__5O__2·2CH__4O__3S = 539.58 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 82956-11-4
Related CAS RN 81525-10-2
Reaxys Registry Number 5703937
PubChem Substance ID 253661919
Merck Index (14) 6350
MDL Number

MFCD00941430

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 95.0 %
Properties (reference)
Melting Point 258 °C
Solubility in water Soluble
Solubility (insoluble in) Ether, Acetone
GHS
Signal Word Warning
Hazard Statements H303 : May be harmful if swallowed.
Precautionary Statements P312 : Call a POISON CENTER/doctor if you feel unwell.
Related Laws:
RTECS# DG2736000
Transport Information:
Customs Control Conditions (Q)
Application
セリンプロテアーゼ阻害剤,ナファモスタットメシル酸塩

Nafamostat mesilate was first reported by Fujii and Hitomi in 1981 as a synthetic serine protease inhibitor. This compound inhibits various serine protease generated during the coagulation cascade and the inflammatory process. Nafamostat mesilate has been commonly used as an anticoagulant and reported as a drug for the treatments of DIC (disseminated intravascular coagulation) and acute pancreatitis and as an anticoagulant in extracorporeal circulation. (The product is for research purpose only.)

References


PubMed Literature


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