Maximum quantity allowed is 999
Please select the quantity
CAS RN: 55481-88-4 | Product Number: M3091
Mollugin
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- Methyl 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
- 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylic Acid Methyl Ester
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 10MG |
¥350.00
|
1 | Contact Us | 9 |
| 50MG |
¥955.00
|
Contact Us | Contact Us | 4 |
* For order or inquiry, please contact
Our Authorized Distributors.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
| Product Number | M3091 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__6O__4 = 284.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 55481-88-4 |
| Reaxys Registry Number | 1433506 |
| PubChem Substance ID | 468592264 |
| MDL Number | MFCD02752331 |
Specifications
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 130.0 to 134.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 132 °C |
| Maximum Absorption Wavelength | 392(MeOH) nm |
GHS
Related Laws:
Transport Information:
| Customs Control Conditions (Q) |
Application
Mollugin: A Crude Medicine Ingredient Contained in a Traditional Chinese Medical Plant, Rubia cordifolia L.
Mollugin is a naphthohydroquine originally isolated from the root of the traditional Chinese medical plant Rubia cordifolia L.1) It has been reported to have a variety of biological activities, including anti-inflammatory activity2,3), neuroprotective activity3), antitumor activity4,5), and inhibitory activity in arachidonic acid- and collagen-induced platelet aggregation.6) (The product is for research purpose only.)
References
- 1)An effective high-speed countercurrent chromatographic method for preparative isolation and purification of mollugin directly from the ethanol extract of the Chinese medicinal plant Rubia cordifolia
- 2)Anti-inflammatory action of mollugin and its synthetic derivatives in HT-29 human colonic epithelial cells is mediated through inhibition of NF-κB activation
- 3)Neuroprotective and anti-inflammatory effects of mollugin via up-regulation of heme oxygenase-1 in mouse hippocampal and microglial cells
- 4)Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL
- 5)Mollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathways
- 6)Antiplatelet constituents of Formosan Rubia alkane
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.