Maximum quantity allowed is 999
Please select the quantity
CAS RN: 5142-23-4 | Product Number: M2518
3-Methyladenine
×
![]()
×
Purity:
Synonyms:
- 6-Amino-3-methylpurine
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 200MG |
¥270.00
|
15 | 1 | ≥60 |
| 1G |
¥730.00
|
Contact Us | 1 | 30 |
* For order or inquiry, please contact
Our Authorized Distributors.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
Properties (reference)
| Melting Point | 300 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | AU6520000 |
Transport Information:
| Customs Control Conditions (Q) |
Application
3-Methyladenine (3-MA): A PI3K inhibitor - An Autophagy Inhibitor
3-Methyladenine (3-MA) inhibits phosphoinositide 3-kinases (PI3K) such as wortmannin [W0007], and is generally used as an inhibitor of autophagy which is an intracellular degradation system that delivers cytoplasmic constituents to the lysosome. Recently, in addition to its role in autophagy, 3-MA has been implicated in cancer research. (The product is for research purpose only.)
References
- 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
- 3-Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism
- 3-Methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions
- Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
- Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
- Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.