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CAS RN: 147591-46-6 | Product Number: I1108
ID 8
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Purity: >98.0%(GC)
Synonyms:
- 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 10MG |
¥240.00
|
1 | Contact Us | 14 |
| 50MG |
¥1,120.00
|
Contact Us | Contact Us | 20 |
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| Product Number | I1108 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__4N__2O__4 = 298.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 147591-46-6 |
| Reaxys Registry Number | 5825601 |
| PubChem Substance ID | 468592099 |
| MDL Number | MFCD00593367 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 266 °C(dec.) |
GHS
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Application
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) Inhibitor
ID 8 (1) was reported as an indole derivative that can sustain embryonic stem cell self-renewal in long-term culture.1)1 inhibits dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2) 1 supports Wnt-induced human embryonic stem cell proliferation and survival without fibroblast growth factor (FGF) and tumor growth factor-β (TGF-β) supplementation.2)
References
- 1) Indole derivatives sustain embryonic stem cell self-renewal in long-term culture
- 2) Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion
Articles/Brochures
TCIMAIL
[TCIMAIL No.188] Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) InhibitorProduct Documents (Note: Some products will not have analytical charts available.)
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Specifications
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