Maximum quantity allowed is 999
CAS RN: 154598-52-4 | Product Number: E0997
Efavirenz
Purity: >98.0%(HPLC)(N)
- (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 5G |
¥760.00
|
2 | 1 | ≥60 |
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Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | E0997 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__4H__9ClF__3NO__2 = 315.68 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 154598-52-4 |
| Reaxys Registry Number | 7387333 |
| PubChem Substance ID | 253660107 |
| Merck Index (14) | 3521 |
| MDL Number | MFCD05662344 |
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 136.0 to 140.0 °C |
| Specific rotation [a]20/D | -93.0 to -98.0 deg(C=1,MeOH) |
| Melting Point | 138 °C |
| Specific Rotation | -95° (C=1,MeOH) |
| Maximum Absorption Wavelength | 247(MeOH) nm |
| Solubility in water | Insoluble |
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
| RTECS# | DM3440000 |
| Customs Control Conditions (Q) |
References
- Efavirenz
- Structural Basis for the Resilience of Efavirenz (DMP-266) to Drug Resistance Mutations in HIV-1 Reverse Transcriptase
- The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism:Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity
- Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance
- The history of antiretrovirals: key discoveries over the past 25 years
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