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CAS RN: 99469-99-5 | Product Number: E0928
2-(3-Ethoxy-4-ethoxycarbonylphenyl)acetic Acid
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Purity: >98.0%(GC)(T)
Synonyms:
- Ethyl 4-Carboxymethyl-2-ethoxybenzoate
- 4-Carboxymethyl-2-ethoxybenzoic Acid Ethyl Ester
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 5G |
¥430.00
|
1 | Contact Us | 2 |
| 25G |
¥2,030.00
|
Contact Us | Contact Us | 6 |
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| Product Number | E0928 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__3H__1__6O__5 = 252.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 99469-99-5 |
| Reaxys Registry Number | 8210175 |
| PubChem Substance ID | 253659996 |
| MDL Number | MFCD08704233 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 78.0 to 82.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 80 °C |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H318 : Causes serious eye damage. |
| Precautionary Statements | P280 : Wear eye protection/ face protection. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
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Application
A Synthetic Intermediate of Repaglinide
This product is used for the synthesis of a carbamoylmethyl benzoic acid derivative, repaglinide [R0179] which is a fast-acting insulin-releasing agent used for the treatment of type 2 diabetes.
References
- Repaglinide and Related Hypoglycemic Benzoic Acid Derivatives
- Studies on diastereofacial selectivity of a chiral tert-butanesulfinimines for the preparation of (S)-3-methyl-1-(2-piperidin-1-yl-phenyl)butylamine for the synthesis of repaglinide
- Identification, isolation, and synthesis of seven novel impurities of anti-diabetic drug Repaglinide
PubMed Literature
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Specifications
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