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CAS RN: 5928-25-6 | Product Number: D6144
Decursin
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Purity: >95.0%(HPLC)
Synonyms:
- (S)-8,8-Dimethyl-2-oxo-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-7-yl 3-Methylbut-2-enoate
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 25MG |
¥2,390.00
|
4 | Contact Us | 16 |
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| Product Number | D6144 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__0O__5 = 328.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 5928-25-6 |
| Reaxys Registry Number | 1626397 |
| MDL Number | MFCD00272154 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 110.0 to 114.0 °C |
| Specific rotation | +138 to +148 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 112 °C |
GHS
Related Laws:
| RTECS# | EM9252405 |
Transport Information:
| Customs Control Conditions (Q) |
Application
Decursin: A Phytochemical with Anticancer and Diverse Biological Activities
Decursin is a phytochemical originally isolated from the roots of Angelica gigas Nakai which is a major medicinal herb in Asian countries such as Korea and China.1) Traditionally, its dried root has been used to treat anemia, pain, infections and articular rheumatism. The extract from the herb, decursin, has diverse biological activities. There are reports that decursin is an anti-inflammatory, anticancer, and neuroprotective agent.1-3) Decursin is also a potent protein kinase C (PKC) activator, and induces apoptosis and cell cycle arrest in G1 phase.4,5) (The product is for research purpose only.)
References
- 1) Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds (a review)
- 2) Decursin and decursinol angelate: molecular mechanism and therapeutic potential in inflammatory diseases (a review)
- 3) Neuroprotective and cognitive enhancement potentials of Angelica gigasnakai root: a review
- 4) Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas
- 5) A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells
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