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CAS RN: 56-25-7 | Product Number: C0019
Cantharidin
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Purity: >98.0%(GC)
Synonyms:
- exo-1,2-cis-Dimethyl-3,6-epoxyhexahydrophthalic Anhydride
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 25MG |
¥370.00
|
1 | Contact Us | Contact Us |
| 100MG |
¥865.00
|
6 | Contact Us | ≥60 |
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| Product Number | C0019 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2O__4 = 196.20 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 56-25-7 |
| Reaxys Registry Number | 85302 |
| PubChem Substance ID | 125308680 |
| Merck Index (14) | 1752 |
| MDL Number | MFCD00134968 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 215.0 to 219.0 °C |
Properties (reference)
| Melting Point | 217 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. H331 : Toxic if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H335 : May cause respiratory irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| CN Number | 1349 |
| RTECS# | RN8575000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | I |
| Customs Control Conditions (Q) |
Application
Cantharidin: A Strong Inhibitor of Protein Phosphatases Types 1 (PP1) and 2A (PP2A)
Cantharidin is a toxic terpenoid compound in the blood of blister beetles. Cantharidin acts as a strong inhibitor of protein phosphatases types 1 (PP1) and 2A (PP2A) which are enzymes that remove a phosphate group from the phosphorylated amino acid residue of its substrate protein. Cantharidin has been used to reat warts and molluscum as a traditional medicine. Recently, several studies have demonstrated that cantharidin has anticancer, antibiotic, antivirus activities and immune-regulated functions. (The product is for research purpose only.)
References
- Cantharidin-binding protein: Identification as protein phosphatase 2A
- Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A
- Molecular modes of action of cantharidin in tumor cells
- Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways
- The effects of cantharidin and cantharidin derivates on tumour cells (a review)
- Exploiting protein phosphatase inhibitors based on cantharidin analogues for cancer drug discovery (a review)
PubMed Literature
Articles/Brochures
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