CAS RN: 469865-01-8 | Product Number: B4339

10,10'-Dimethyl-9,9'-biacridinium Bis(monomethyl Terephthalate) [for Chemiluminescence Research]

Purity:

Synonyms:

Product Documents:

Size	Unit Price	Shanghai	Tianjin	Japan*
100MG	¥390.00	1	Contact Us	3
1G	¥1,665.00	1	Contact Us	6

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General Information plus

Product Number	B4339
Molecular Formula / Molecular Weight	C__4__6H__3__6N__2O__8 = 744.80
Physical State (20 deg.C)	Solid
Storage Temperature	Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN	469865-01-8
PubChem Substance ID	354333192

Specifications & Documents plus

Specifications

Appearance	Yellow to Amber to Dark red powder to crystal
Chemiluminescence test (Superoxide radical)	to pass test
NMR	confirm to structure

Properties (reference)

Safety & Properties plus

GHS

Pictogram
Signal Word	Warning
Hazard Statements	H315 : Causes skin irritation. H319 : Causes serious eye irritation.
Precautionary Statements	P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention.

Related Laws:

Transport Information:

Customs Control Conditions (Q)

Applications & Literature plus

Application

Chemiluminescence Reagent for the Detection of Intramitochondrial Superoxide

MMT, developed by Kobayashi et al., is a lucigenin derivative, which is a specific probe having green chemiluminescence to superoxide among reactive oxygen species. Since amphiphilic MMT which is less hydrophilic than lucigenin possesses cell-permeability, MMT has been applicable for the detection of intramitochondrial superoxide production. Figure 1 shows the localization of MMT in mitochondria in mouse peritoneal neutrophils.

References

Specific detection of intramitochondrial superoxide produced by either cell activation or apoptosis by employing a newly developed cell-permeative lucigenin derivative, 10,10'-dimethyl-9,9'-biacridinium bis(monomethyl terephthalate)
- S. Sasaki, S. Yamada, M. Iwamura, Y. Kobayashi, Free Radic. Biol. Med. 2013, 65, 1005.