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Modified HSA for Click Chemistry
No.189(March 2022)
HSA-DBCO (1) is a complex of human serum albumin (HSA) and dibenzocyclooctyne (DBCO) moiety, which is used as a linker for the copper-free click reaction. 1 easily reacts with azide compounds to form a conjugate by just mixing.1,2) Generally, HSA can be coated on a variety of plates and material surfaces, so 1 can be used to prepare conjugated products for various types of experiments.
References
- 1) Bioorthogonal chemistry for 68Ga radiolabelling of DOTA-containing compounds
- 2) From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions
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