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CAS RN: 152121-53-4 | Product Number: P2532
PD 169316
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Purity: >98.0%(HPLC)
Synonyms:
- 4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
- 4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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|---|---|---|---|---|---|
| 10MG |
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|
14 | 0 | Contact Us | |
| 50MG |
A$1,247.00
|
25 | 4 | Contact Us |
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| Product Number | P2532 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__1__3FN__4O__2 = 360.35 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 152121-53-4 |
| Reaxys Registry Number | 7660816 |
| PubChem Substance ID | 354335509 |
| MDL Number | MFCD12405019 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 14.70 to 16.30 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
A p38 MAPK inhibitor
PD169316 is a selective inhibitor of p38 mitogen-activated protein kinase (MAPK) that plays an important role in signal transduction.
References
- Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase
- The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor β-induced Smad signaling in human ovarian cancer cells
PubMed Literature
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