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CAS RN: 137-58-6 | Product Number: L0156

Lidocaine


Purity: >99.0%(T)(HPLC)
Synonyms:
  • 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Product Documents:
25G
A$110.00
14   ≥80 
100G
A$307.00
14   26  
500G
A$908.00
15   ≥80 
* Please contact our distributor of Chem-Supply if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* ChemSupply Australia Pty Ltd (Phone: 08-8440-2000 / email:  sales@chemsupply.com.au)

Product Number L0156
Purity / Analysis Method >99.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__4H__2__2N__2O = 234.34 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive
CAS RN 137-58-6
Reaxys Registry Number 2215784
PubChem Substance ID 87572107
SDBS (AIST Spectral DB) 27423
Merck Index (14) 5482
MDL Number

MFCD00026733

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 99.0 area%
Purity(Nonaqueous Titration) min. 99.0 %
Melting point 66.0 to 70.0 °C
Solubility in Methanol almost transparency
Properties (reference)
Melting Point 69 °C
Boiling Point 182 °C/4 mmHg
Solubility in water Insoluble
Degree of solubility in water 410 mg/l   30 °C
Solubility (soluble in) Alcohol, Benzene, Ether, Chloroform
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H362 : May cause harm to breast-fed children.
H370 : Causes damage to organs.
H372 : Causes damage to organs through prolonged or repeated exposure.
H317 : May cause an allergic skin reaction.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P263 : Avoid contact during pregnancy/ while nursing.
P272 : Contaminated work clothing should not be allowed out of the workplace.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# AN7525000
Transport Information:
H.S.code* 2924.29-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Lidocaine: A Voltage Gated Sodium Channel Blocker

Lidocaine is widely used for regional anesthesia and postoperative pain relief, and these effects involve the blockade of voltage-dependent sodium channels which play a key role in the pathogenesis of neuropathic pain. Thus, lidocaine stabilizes the neuronal cell membrane by inhibiting the movement of sodium ions into a nerve cell. Lignocaine is also a class IB antiarrhythmic agent as a sodium channel blocker. Lidocaine is metabolized rapidly by CYP1A2 and CYP3A4 in liver to main active metabolites, monoethylglycine xylidide (MEGX) [N1171] and glycinexylidide (GX) [G0579]. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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