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CAS RN: 58306-30-2 | Product Number: F0922
Febantel
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Product Number | F0922 |
Molecular Formula / Molecular Weight | C__2__0H__2__2N__4O__6S = 446.48 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 58306-30-2 |
Reaxys Registry Number | 13258677 |
PubChem Substance ID | 253661507 |
Merck Index (14) | 3944 |
MDL Number | MFCD01738527 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(with Total Nitrogen) | min. 98.0 % |
Melting point | 125.0 to 129.0 °C |
Properties (reference)
Melting Point | 130 °C |
Solubility in water | Insoluble |
GHS
Related Laws:
RTECS# | FB3955000 |
Transport Information:
H.S.code* | 2930.90-900 |
Application
Febantel: A Broad-Spectrum Pro-Benzimidazole Anthelminthic
Febantel is a veterinary anthelmintic belonging to the chemical class of the benzimidazoles, but is a so-called pro-benzimidazole. Febantel itself has no anthelmintic properties. It is transformed into active fenbendazole and fenbendazole sulfoxide (= oxfendazole) in the host's liver. It is highly active against various species of nematodes and cestodes in mice, rats, dogs, sheep, and cattle. Recently, Febantel is often used in combination with other anthelmintics (pyrantel pamoate and etc.). (The product is for research purpose only.)
References
- Febantel, a new broad-spectrum anthelminthic
- H. Wollweber, H. Koelling, A. Widdig, H. Thomas, H. P. Schulz, P. Muermann, Arzneim.-Forsch. 1978, 28, 2193.
- In vitro febantel transformation by sheep and cattle ruminal fluids and metabolism by hepatic subcellular fractions from different animal species
- Efficacy of a drug combination of praziquantel, pyrantel pamoate, and febantel against giardiasis in dogs
- S. C. Barr, D. D. Bowman, M. F. Frongillo, S. L. Joseph, Am. J. Vet. Res. 1998, 59, 1134.
- Rapid determination of the antiparasitic drugs flubendazole and febantel in feeds by HPLC with ultraviolet detection
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