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CAS RN: 144060-53-7 | Product Number: F0847

Febuxostat


Purity: >97.0%(T)(HPLC)
Synonyms:
  • 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid
Product Documents:
1G
A$228.00
21   ≥80  Contact Us
5G
A$664.00
28   2   Contact Us
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Product Number F0847
Purity / Analysis Method >97.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__1__6N__2O__3S = 316.38 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 144060-53-7
Reaxys Registry Number 8005333
PubChem Substance ID 172089002
Merck Index (14) 3948
MDL Number

MFCD00871598

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Neutralization titration) min. 97.0 %
Melting point 207.0 to 211.0 °C
Properties (reference)
Melting Point 209 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
Related Laws:
RTECS# XJ3675310
Transport Information:
H.S.code* 2934.10-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Studies on the Inhibition of Xanthine Oxidoreductase, Febuxostat

References


Application
Febuxostat: A Non-Purine Selective Xanthine Oxidase (XO) Inhibitor

Febuxostat (TEI-6720) is a non-purine selective xanthine oxidase (XO) inhibitor. Uric acid [U0018] is the end product of purine metabolism in humans and is generated in the cascade of hypoxanthine [H0311] → xanthine [X0004] → uric acid. The both transformations are catalyzed by XO. Febuxostat is a XO inhibitor that significantly reduces uric acid levels in blood and urine. Therefore, in clinical, febuxostat is used for the treatment of hyperuricemia and gout. For your reference, [E1049] [E1394] and [E1414] are synthetic intermediates of febuxostat. (The product is for research purpose only.)

References


PubMed Literature


Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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