TCI Chemistry News
Maximum quantity allowed is 999
Please select the quantity
April 2023
TCI offers an extensive catalog of over 30,000 high quality organic reagents suitable for benchtop-to-bulk chemistry. This issue covers our chemistry topics as follows:
- Ligands for Reductive Cross-Electrophile Coupling (CEC)
- Fluorination of an Alcohol Using DAST
- Hartwig-Miyaura C-H Borylation Using an Iridium Catalyst
- Palladium Complex Catalyzing the Suzuki-Miyaura Coupling Reactions of Heteroaryl Chlorides
- Printed Magazine: TCIMAIL 192
Ligands for Reductive Cross-Electrophile Coupling (CEC)
C(sp2)-C(sp3) cross-coupling reactions have been intensively studied in recent years. The reactions allow the introduction of alkyl groups into aromatic rings. Among the reactions, the cross-coupling reactions of aryl halides with alkyl halides and redox-active aliphatic carboxylic acids, etc., are known as reductive cross-electrophile couplings (CEC). TCI has five ligands for reductive cross-electrophile couplings [P3015], [D6070], [P2176], [C3801], [C3803]. These ligands can be used in reductive cross electrophile couplings with nickel catalysts and metal powders as reducing agents. Bipyridyl ligands have been known to catalyze this reaction, but the ligands bearing carboxamidine group gives better results with some substrate combinations. These carboximidamide-containing ligands with different properties and structures are useful for screening catalytic systems to match the desired reaction substrates.
TCI Practical Example:Fluorination of an Alcohol Using DAST
We are proud to present the conversion from the hydroxyl group of 4-nitrobenzyl alcohol to a fluorine group by using DAST [D1868] as a deoxofluorination reagent. You can also see other fluorination reagents in TCI product brochure.
TCI Practical Example: Hartwig-Miyaura C-H Borylation Using an Iridium Catalyst
TCI introduces the C-H borylation of benzo[1,2-b:4,5-b']dithiophene with bis(pinacolato)diboron in the presence of [Ir(cod)OMe]2 [C2662] as a catalyst. The direct borylation of aromatic compounds proceeds in combination with an iridium catalyst and an electron-donating bipyridine ligand.
Palladium Complex Catalyzing the Suzuki-Miyaura Coupling Reactions of Heteroaryl Chlorides
Pd(Amphos)2Cl2 [B6255] is an air-stable divalent palladium(II) complex that efficiently catalyzes Suzuki-Miyaura coupling reaction. The reaction is applicable to substrates with heteroatom-containing groups (such as heteroaryl chlorides, thiol, amino, alkoxy amino and alkoxy groups) which can be catalyst poisons. In addition, the complex exhibits higher turnover numbers (TONs).
Printed Magazine: TCIMAIL 192
Released in March 2023, TCI's latest issue features Assoc. Prof. Masaki Ohtawa’s article and Prof. Nagatoshi Nishiwaki’s chemistry chat. We also feature research on:- Hydroxyamine Derivative for the Amination of Alkenes and Thiols
- Guaranteed Analytical Reagents for Oligonucleotides
- Imidazolium Salts as Coupling Activators for Oligonucleotide Synthesis
- A Monomer Used for Developing Mussel-Inspired Dry/Wet Adhesives
- Glycoprotein Capturing Reagents: Lectin-Immobilized Agarose "LecBeads"
- Histone Methyl Transferase (HMTase) Inhibitor
- AMP-Activated Protein Kinase (AMPK) Activator
Upcoming Events
2023 Annual Spring meeting of the Polymer Society of Korea
April 5-7, 2023
Daejeon Convention Center (DCC), Korea
April 5-7, 2023
Daejeon Convention Center (DCC), Korea
131th General Meeting of the Korean Chemical Society
April 26-28, 2023
Suwon Convention Center (SCC), Korea
April 26-28, 2023
Suwon Convention Center (SCC), Korea
How to Order TCI ProductsTo order, please contact your local distributor found below.» Our distributors |
| * The prices displayed in the landing website are USD based catalog prices. TCI has specific website and local currency based price list for customers in South Korea, Singapore, and Australia. For customers in other Asia Pacific countries / regions, please visit our Asia Pacific Website and contact our local distributors for the end user's cost. (The USD prices that are shown in Asia Pacific websites are TCI's catalog prices.) Please visit each country/region's website from the following links and confirm the prices. https://www.TCIchemicals.com |
|
If you are interested in our biweekly e-enewsletter "TCI News" and want to receive regularly, please click the link below and sign up. TCI News Sign-Up |
|
Tokyo Chemical Industry Co., Ltd. (TCI) Global Business Department Customer Support and Technical service » globalbusiness@TCIchemicals.com » https://www.TCIchemicals.com |