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CAS RN: 58-39-9 | Product Number: P1970
Perphenazine
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
- 4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$58.00
|
Contact Us | 1 | 17 |
|
| 25G |
$172.00
|
Contact Us | Contact Us | 7 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P1970 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__6ClN__3OS = 403.97 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 58-39-9 |
| Reaxys Registry Number | 54730 |
| PubChem Substance ID | 253660321 |
| Merck Index (14) | 7183 |
| MDL Number | MFCD00056798 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 95.0 to 99.0 °C |
Properties (reference)
| Melting Point | 97 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 28.3 mg/l 24 °C |
| Solubility (soluble in) | Acetone, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | TL7175000 |
Transport Information:
| HS Number | 2934.30.5000 |
Application
Perphenazine: A Classical Phenothiazine Typical Antipsychotic
Perphenazine is a classical phenothiazine typical antipsychotic with a potency similar to haloperidol [H0912], a dopamine antagonist. It is extensively metabolized in the liver to a number of metabolites. The pharmacokinetics of perphenazine is mediated by cytochrome P450 2D6 (CYP2D6) and thus is subject to genetic polymorphism. It induces cleft palate in mice fetuses. (The product is for research purpose only.)
References
- Perphenazine (Trilafon) Metabolism in Psychotic Patients
- Steady-state serum concentrations of the neuroleptic perphenazine in relation to CYP2D6 genetic polymorphism
- Pharmacogenetics of classical and new antipsychotic drugs
- Reduction of Drug-Induced Cleft Palate in Mice
PubMed Literature
Articles/Brochures
TCIMAIL
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