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CAS RN: 1665-48-1 | 产品编码: M2578
Metaxalone
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| 产品编码 | M2578 |
纯度/分析方法 
|
>98.0%(GC) |
| 分子式/分子量 | C__1__2H__1__5NO__3 = 221.26 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 1665-48-1 |
| Reaxys-RN | 884592 |
| PubChem物质ID | 253662077 |
| MDL编号 | MFCD00867700 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 122.0 to 126.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 124 °C |
| 沸点 | 225 °C/1.5 mmHg |
| 水溶性 | 不溶 |
| 在水中的溶解度 | 91 mg/l 25 °C |
| 溶解性（可溶于） | 乙醇, 甲醇 |
| 溶解性（不溶于） | 乙醚 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | RQ3850000 |
运输信息
| HS编码* | 2934.99-000 |
应用
Metaxalone: A Muscle Relaxant
Metaxalone is a muscle relaxant which is used to relieve pain caused by strains, sprains and other muscle injuries with no defined cellular mechanism of action. Its efficacy has been considered to be due to general central nervous system depression. (The product is for research purpose only.)
References
- Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone (a review)
- Metaxalone (Skelaxin®)-related death
- Quantification of Metaxalone in Human Plasma by Liquid Chromatography Coupled to Tandem Mass Spectrometry
- New stability-indicating RP-HPLC method for determination of diclofenac [D3748] potassium and metaxalone from their combined dosage form
PubMed Literature
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技术规格
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