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Published TCIMAIL newest issue No.197
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CAS RN: 478-43-3 | Product Number: D3986
4,5-Dihydroxyanthraquinone-2-carboxylic Acid
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Purity: >95.0%(T)(HPLC)
Synonyms:
- Rhein
- Cassic Acid
- Rhubarb Yellow
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€17.00
|
Contact Us | 18 |
|
| 1G |
€57.00
|
4 | 11 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D3986 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__8O__6 = 284.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 478-43-3 |
| Reaxys Registry Number | 2222155 |
| PubChem Substance ID | 125307728 |
| Merck Index (14) | 8176 |
| MDL Number | MFCD00009618 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
Properties (reference)
| Melting Point | 321 °C |
| Maximum Absorption Wavelength | 432(MeOH) nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 207-521-4 |
| RTECS# | CA9516000 |
Transport Information:
| HS Number | 2918999090 |
Application
Bone research
References
- Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling
- Diacerhein and rhein reduce the ICE-induced IL-1β and IL-18 activation in human osteoarthritic cartilage
Application
Rhein; A Bioactive Anthraquinone Isolated from Rheum palmatum L.
Rhein is an anthraquinone, isolated from several traditional Chinese medicines, including Rheum palmatum L. It has been reported that rhein exerts various pharmacological activities, such as anti-inflammatory, antitumor, antioxidant, antifibrosis, hepatoprotective, and nephroprotective activities. (The product is for research purpose only.)
References
- Anti-cancer properties of anthraquinones from Rhubarb (a review)
- A comprehensive and system review for the pharmacological mechanism of action of rhein, an active anthraquinone ingredient (a review)
- Research Progress on the Antitumor Effects of Rhein: Literature Review
- Pharmacokinetic analysis of rhein in Rheum undulatum L
PubMed Literature
Articles/Brochures
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