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Published TCIMAIL newest issue No.197
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CAS RN: 138890-62-7 | Product Number: B4258
Brinzolamide
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Purity: >98.0%(HPLC)
Synonyms:
- (R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€28.00
|
1 | 9 |
|
| 100MG |
€94.00
|
1 | ≥60 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B4258 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__2__1N__3O__5S__3 = 383.50 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 138890-62-7 |
| Reaxys Registry Number | 9651552 |
| PubChem Substance ID | 253660292 |
| Merck Index (14) | 1376 |
| MDL Number | MFCD08067749 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 130.0 to 134.0 °C |
Properties (reference)
| Melting Point | 132 °C |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | XJ9095055 |
Transport Information:
| HS Number | 2935909099 |
Application
Brinzolamide: A Specific Carbonic Anhydrase (CA) II Inhibitor
Brinzolamide is a specific carbonic anhydrase (CA) inhibitor specifically carbonic anhydrase II. It lowers intraocular pressure (IOP) by reducing the rate of aqueous humor formation (AHF). (The product is for research purpose only.)
References
- Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors
- Brinzolamide (a review of its use in the management of primary open-angle glaucoma and ocular hypertension)
- Brinzolamide (a review)
- Brinzolamide/timolol (in open-angle glaucoma and ocular hypertension)
- Brinzolamide/timolol fixed combination: a new ocular suspension for the treatment of open-angle glaucoma and ocular hypertension
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Articles/Brochures
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