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CAS RN: 667463-62-9 | Product Number: B4006
(2'Z,3'E)-6-Bromoindirubin-3'-oxime
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Purity: >95.0%(HPLC)
Synonyms:
- BIO
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5MG |
€79.00
|
1 | 3 |
|
| 25MG |
€253.00
|
1 | 1 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B4006 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__0BrN__3O__2 = 356.18 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 667463-62-9 |
| Reaxys Registry Number | 9653830 |
| PubChem Substance ID | 172089031 |
| MDL Number | MFCD08705318 |
Specifications
| Appearance | Orange to Amber to Dark red powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Elemental analysis(Nitrogen) | 11.30 to 12.30 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 300 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | NM3241900 |
Transport Information:
| HS Number | 2933790090 |
Application
Glycogen Synthase Kinase (GSK) Inhibitor
References
- 1)GSK-3-selective inhibitors derived from Tyrian purple indirubins
- 2)Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases
- 3)Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
- 4)The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes
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