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CAS RN: 15421-84-8 | Product Number: T4243
Trapidil
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Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- N,N-Diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
$137.00
|
10 | 0 | It can be shipped in about 2 weeks after ordering | |
| 50MG |
$455.00
|
10 | 0 | It can be shipped in about 2 weeks after ordering |
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* The storage conditions are subject to change without notice.
| Product Number | T4243 |
| Purity / Analysis Method | >98.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__1__0H__1__5N__5 = 205.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 15421-84-8 |
| Reaxys Registry Number | 186842 |
| MDL Number | MFCD00193104 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 100.0 to 104.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 102 °C |
| Solubility (slightly sol. in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | XZ5700000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2933.59-000 |
Application
Trapidil: A Platelet-Derived Growth Factor (PDGF) Antagonist
Trapidil was originally developed as an antiplatelet agent and vasodilator.1,2) Subsequently, trapidil has been reported as a platelet-derived growth factor (PDGF) antagonist with anti-proliferative effects.3,4) (The product is for research use only.)
References
- 1) Effect of trapidil on prostacyclin generation of arterial wall
- 2) Antithrombotic activity and the mechanism of action of trapidil (Rocornal®)
- 3) Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro
- 4) Trapidil Inhibits Platelet-Derived Growth Factor–Stimulated Mitogen-Activated Protein Kinase Cascade
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