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CAS RN: 2826-26-8 | Product Number: T3074
Tyrphostin A1
![Tyrphostin A1 No-Image](/medias/T3074.jpg?context=bWFzdGVyfHJvb3R8MzgxODF8aW1hZ2UvanBlZ3xhRFV5TDJoa015ODRPVEl6TlRVM09EVTFNall5TDFRek1EYzBMbXB3Wnd8NzE3YzViY2UzZWM5OTRmYjliZDI1ODViMjNiMTk5NmZlNWM0MDBiOTVkNzdiMWUxMDUwYzMyYTI4ODFlMDA2ZA)
Purity: >98.0%(GC)
Synonyms:
- Tyrphostin 1
- (4-Methoxybenzylidene)malononitrile
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
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---|---|---|---|---|---|
200MG |
$63.00
|
3 | 1 | Contact Us | |
1G |
$205.00
|
1 | 2 | Contact Us |
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* The storage conditions are subject to change without notice.
Product Number | T3074 |
Purity / Analysis Method | >98.0%(GC) |
Molecular Formula / Molecular Weight | C__1__1H__8N__2O = 184.20 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 2826-26-8 |
Reaxys Registry Number | 1869845 |
PubChem Substance ID | 253662620 |
MDL Number | MFCD00019787 |
Specifications
Appearance | Light orange to Yellow to Green powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 113.0 to 117.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 115 °C |
Maximum Absorption Wavelength | 350(H2O) nm |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
Transport Information:
UN Number | UN3439 |
Class | 6.1 |
Packing Group | III |
H.S.code* | 2926.90-000 |
Application
Kinase Inhibitor
References
- 1)Tyrphostins I: Synthesis and biological activity of rotein tyrosine kinase inhibitors
- 2)Differential requirements for JAK2 and TYK2 in T cell proliferation and IFN-γ production induced by IL-12 alone or together with IL-18
- 3)Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines
- 4)Epidermal growth factor system regulates mucin production in airways
- 5)Enhancement of recombinant adeno-associated virus type 2-mediated transgene expression in a lung epithelial cell line by inhibition of the epidermal growth factor receptor
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