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CAS RN: 89778-27-8 | Product Number: T2832
Toremifene Citrate
Purity: >98.0%(T)(HPLC)
Synonyms:
- (Z)-4-Chloro-1-(4-dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene Citrate
- (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine Citrate
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
1G |
$125.00
|
20 | 2 |
5G |
$389.00
|
16 | 2 |
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* The storage conditions are subject to change without notice.
Product Number | T2832 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__6H__2__8ClNO·C__6H__8O__7 = 598.09 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 89778-27-8 |
Related CAS RN | 89778-26-7 |
Reaxys Registry Number | 8181005 |
PubChem Substance ID | 160871014 |
Merck Index (14) | 9550 |
MDL Number | MFCD01729016 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
Melting Point | 162 °C(dec.) |
Solubility (soluble in) | Methanol |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H302 : Harmful if swallowed. H360 : May damage fertility or the unborn child. H362 : May cause harm to breast-fed children. H413 : May cause long lasting harmful effects to aquatic life. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P273 : Avoid release to the environment. P260 : Do not breathe dusts or mists. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
Related Laws:
Transport Information:
H.S.code* | 2921.49-000 |
Application
Biofilm research
Reference
- Repurposing Toremifene for Treatment of Oral Bacterial Infections
Application
Toremifene Citrate: A Selective Estrogen Receptor Modulator (SERM)
Toremifene citrate is a widely used nonsteroidal anti-estrogen agent for the treatment of hormone-dependent breast cancer. Toremifene is metabolized by cytochrome P450 (CYP450) enzymes into active metabolites N-desmethyltoremifene which has anti-estrogen activity as well. They act as an estrogen receptor antagonist in breast tissue. Tamoxifen is commonly referred to as a selective estrogen receptor modulator (SERM), since it behaves as an estrogen receptor agonist in other tissues. (The product is for research purpose only.)
References
- Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model
- Effects of the antiestrogens tamoxifen, toremifene, and ICI 182,780 on endometrial cancer growth
- Effects of chronic administration of tamoxifen and toremifene on DNA adducts in rat liver, kidney, and uterus
- Pharmacokinetics of selective estrogen receptor modulators (a review)
- Selective estrogen receptor modulators (SERMs): Mechanisms of anticarcinogenesis and drug resistance (a review)
Application
Studies on Materials for Controlled Release of Toremifene Citrate
References
- Silica xerogel as an implantable carrier for controlled drug delivery-evaluation of drug distribution and tissue effects after implantation
- Silica xerogel carrier material for controlled release of toremifene citrate
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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