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CAS RN: 211914-51-1 | Product Number: D5902
Dabigatran
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Purity: >95.0%(HPLC)
Synonyms:
- N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
- 3-[2-[[(4-Carbamimidoylphenyl)amino]methyl]-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido]propanoic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
$164.00
|
6 | 0 | Contact Us | |
| 500MG |
$573.00
|
22 | 0 | Contact Us |
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| Product Number | D5902 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__2__5N__7O__3 = 471.52 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 500MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 211914-51-1 |
| Reaxys Registry Number | 9168207 |
| PubChem Substance ID | 468591632 |
| MDL Number | MFCD09837830 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0% (calcd. on anh. substance) |
| Purity(Volumetric Analysis) | min. 98.0% (calcd. on anh. substance) |
| Water | max. 10.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 270 °C(dec.) |
GHS
Related Laws:
| RTECS# | AY3157700 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Dabigatran: A Reversible Direct Thrombin Inhibitor
Dabigatran is a reversible direct thrombin inhibitor, and an active metabolite of dabigatran etexilate [D5904]. Thrombin enables the conversion of fibrinogen into fibrin during the blood coagulation cascade. The inhibition prevents the development of a thrombus. Therefore, thrombin-induced platelet aggregation are inhibited by the active metabolite, dabigatran. In clinical, it is used as an alternative to warfarin [W0005] and does not require monitoring of blood coagulation parameters by blood tests. (The product is for research purpose only.)
References
- Advancement in antithrombotics for stroke prevention in atrial fibrillation (a review)
- Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity (a review)
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