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CAS RN: 88416-50-6 | Product Number: D4160
Disodium Clodronate Tetrahydrate
Purity: >95.0%(T)
Synonyms:
- Clodronic Acid Disodium Salt Tetrahydrate
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
1G |
$73.00
|
≥40 | 1 |
5G |
$248.00
|
18 | 6 |
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Product Number | D4160 |
Purity / Analysis Method | >95.0%(T) |
Molecular Formula / Molecular Weight | CH__2Cl__2Na__2O__6P__2·4H__2O = 360.91 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 5G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 88416-50-6 |
Related CAS RN | 22560-50-5 |
PubChem Substance ID | 253660294 |
Merck Index (14) | 2371 |
MDL Number | MFCD02940846 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(Neutralization titration) | min. 95.0 % |
Water | 18.0 to 22.0 % |
NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
H.S.code* | 2931.59-000 |
Application
Bone Resorption Inhibitor
References
- 1)Bisphosphonates: From bench to bedside
- 2)Computational insights into binding of bisphosphonates to farnesyl pyrophosphate synthase
- 3)Tumour macrophages as potential targets of bisphosphonates
- 4)Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach
- 5)Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft
- 6)Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages
- 7)Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects
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