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CAS RN: 20362-31-6 | Product Number: A3118
Arctiin
![Arctiin No-Image](/medias/A3118.jpg?context=bWFzdGVyfHJvb3R8NDM0NTl8aW1hZ2UvanBlZ3xhRGxtTDJoak15ODRPVEU1TnpJM01ERXpPVEU0TDBFek1URTRMbXB3Wnd8YjllNTcyMDVjYjU3ZDNjOGQ4OTRlNzc3NWI5ZDg2YTkxNTJkYmM0ZGFmZWUyODcxODc5ZmZhMDYxZTc4N2ZkZg)
Purity: >97.0%(HPLC)
Synonyms:
- Arctigenin-4-glucoside
- (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]-3-[[4-(β-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-2(3H)-furanone
Product Documents:
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Product Number | A3118 |
Purity / Analysis Method | >97.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__7H__3__4O__1__1 = 534.56 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 20362-31-6 |
Reaxys Registry Number | 4218850 |
PubChem Substance ID | 354335191 |
MDL Number | MFCD00870630 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 97.0 area% |
Specific rotation [a]20/D | -51.0 to -56.0 deg(C=2, MEOH) |
Properties (reference)
Melting Point | 109 °C |
Specific Rotation | -53° (C=2,MeOH) |
Maximum Absorption Wavelength | 278(EtOH) nm |
GHS
Related Laws:
Transport Information:
H.S.code* | 2938.90-000 |
Application
Arctiin: A Lignin with Wide Pharmacological Actions
Arctigenin [A3117] and its glycoside, arctiin, are lignans found in many plants of Arctium lappa L. (AL, family Asteraceae).1,2) They reportedly have wide pharmacological actions, such as antitumor3,4), anti-inflammatory5), and antiviral6) actions. In addition, the emission spectra of arctiin by fluorescence spectrometry has been reported.7) (The product is for research purpose only.)
References
- 1)Application of preparative high-speed counter-current chromatography for separation and purification of arctiin from Fructus Arctii
- 2)Isolation and identification of arctiin and arctigenin in leaves of burdock (Arctium lappa L.) by polyamide column chromatography in combination with HPLC-ESI/MS
- 3)Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa
- 4)Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats
- 5)Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways
- 6)Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus
- 7)Studies on the arctiin and its interaction with DNA by spectral methods (a review)
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