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CAS RN: 255906-59-3 | 產品號碼: V0173
VK3-OCH3
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| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 50MG |
NT$12,600
|
17 | 0 | 下單後約3-4週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
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產品規格
| Appearance | Light yellow to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 66.0 to 70.0 °C |
| NMR | confirm to structure |
性質
GHS
相關法規
運輸資料
| HS編碼* | 2930.90-900 |
Application
VK3-OCH3: A Thioether Analog of Vitamin K with a Selective Anti-Tumor Activity
VK3-OCH3 is a thioether analog of vitamin K with a selective anti-tumor activity.1-3) It has been reported that VK3-OCH3 inhibits the activity of protein-tyrosine phosphatases (PTPases), and induces protein-tyrosine phosphorylation in a human hepatoma cell line (Hep3 B).1) In another report, VK3-OCH3 induces G2/M arrest and apoptosis through heme oxygenase-1 (HO-1) related signal transduction in neuroblastoma cells and exhibit less cytotoxicitiy in normal cell lines.2) (The product is for research purpose only.)
References
- 1) Inhibition of hepatoma cell growth in vitro by arylating and non-arylating K vitamin analogs. Significance of protein tyrosine phosphatase inhibition
- 2) Vitamin K3 Analogs Induce Selective Tumor Cytotoxicity in Neuroblastoma
- 3) Synthesis, anticancer activity, and molecular modeling of 1,4-naphthoquinones that inhibit MKK7 and Cdc25
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