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CAS RN: 50700-72-6 | 產品號碼: V0120
Vecuronium Bromide
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補充產品訊息:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| 產品號碼 | V0120 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__3__4H__5__7BrN__2O__4 = 637.74 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (<0°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 50700-72-6 |
| Reaxys-RN | 4106207 |
| PubChem Substance ID | 253660212 |
| Merck Index(14) | 9941 |
| MDL編號 | MFCD00867762 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +31.0 to +34.0 deg(C=1, 0.05mol/L HCl) |
| Water | max. 4.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 235 °C(dec.) |
| 比旋光 [α]D | 32° (C=1,0.05mol/L HCl) |
| 溶解性（不溶於） | Ether |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | TN4875000 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
Vecuronium Bromide: a Nicotinic Acetylcholine Receptor Antagonist
Vecuronium bromide is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide has antagonistic properties that target the neuromuscular nicotinic acetylcholine receptor.
References
- Structure:action relationships among some desacetoxy analogues of pancuronium and vecuronium in the anesthetized cat
- Nicotinic antagonist-produced frequency-dependent changes in acetylcholine release from rat motor nerve terminals
- The actions of muscle relaxants at nicotinic acetylcholine receptor isoforms
- Additive inhibition of nicotinic acetylcholine receptors by corticosteroids and the neuromuscular blocking drug vecuronium
- The potency of new muscle relaxants on recombinant muscle-type acetylcholine receptors
考研文獻
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