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CAS RN: 83480-29-9 | 產品號碼: V0119
Voglibose
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產品號碼 | V0119 |
純度/分析方法 | >98.0%(T)(HPLC) |
分子式 / 分子量 | C__1__0H__2__1NO__7 = 267.28 |
外觀與形狀(20°C) | Solid |
儲存條件 | Frozen (<0°C) |
應避免的情況 | Heat Sensitive |
包裝和容器 | 100MG-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 83480-29-9 |
Reaxys-RN | 5430708 |
PubChem Substance ID | 160871113 |
Merck Index(14) | 10029 |
MDL編號 | MFCD00865496 |
產品規格
Appearance | White to Almost white powder to crystal |
Purity(HPLC)(CAD) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 163.0 to 168.0 °C |
Specific rotation [a]20/D | +45.0 to +48.0 deg(C=1、0.1mol/LHCl |
性質
熔點 | 165 °C |
比旋光 [α]D | 46° (C=1,0.1mL/L HCl) |
GHS
相關法規
RTECS # | NM7524600 |
運輸資料
HS編碼* | 2922.19-000 |
Application
Voglibose: A Pseudo-Monosaccharide α-Glucosidase Inhibitor
Voglibose (AO-128) is a pseudo-monosaccharide α-glucosidase inhibitor, such as miglitol [M2302]. α-Glucosidase (also called maltase) is an enzyme, and catalyzes the hydrolysis of terminal 1,4-linked α-glucose residues of oligosaccharides and disaccharides to a single α-glucose molecule. Miglitol lowers blood sugar by inhibiting the enzyme α-glucosidase in the gastrointestinal tract, resulting in delayed glucose absorption. In addition, α-glucosidase inhibitors do not stimulate insulin release and therefore do not result in hypoglycemia. (The product is for research purpose only.)
References
- Synthesis and α-D-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents
- Voglibose (Basen, AO-128), one of the most important α-glucosidase inhibitors (a review)
- Voglibose: an alpha glucosidase inhibitor (a review)
- Quantitative determination of voglibose in pharmaceutical tablets using high-performance liquid chromatography-fluorescence detection with post-column derivatization and mass spectrometric detection
考研文獻
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