Maximum quantity allowed is 999
请选择数量
CAS RN: 192185-72-1 | 產品號碼: T4299
| 產品號碼 | T4299 |
純度/分析方法 
|
>95.0%(HPLC) |
| 分子式 / 分子量 | C__2__7H__2__2Cl__2N__4O = 489.40 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Frozen (-20°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 192185-72-1 |
| Reaxys-RN | 9734901 |
| MDL編號 | MFCD07772347 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 214.0 to 218.0 °C |
| Specific rotation | +20.0 to +24.0 deg(C=1, methanol) |
| NMR | confirm to structure |
性質
| 熔點 | 216 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H373 : May cause damage to organs through prolonged or repeated exposure. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P314 : Get medical advice/ attention if you feel unwell. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
| RTECS # | VC8274507 |
運輸資料
| HS編碼* | 2933.79-000 |
Application
Tipifarnib: A Potent and Selective Inhibitor of Farnesyl Transferase
Farnesyl transferase (FT) regulates the activation of the Ras protein, which consequently affects intracellular signal transduction, cell growth, and proliferation. Tipifarnib (R115777) has been reported to be a potent and selective inhibitor of FT, exhibiting significant antitumor effects in vivo and in vitro. (The product is for research use only.)
References
- Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro
- Farnesyl protein transferase inhibitor ZARNESTRA R115777 - history of a discovery (a review)
- Development of farnesyl transferase inhibitors: a review
- Farnesyl transferase inhibitors (a review)
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）
SDS
請選擇語言。
請求的SDS不可用。
如需更多幫助，請聯繫我們 。
產品規格
檢驗報告(CoA)及其他文檔
請輸入批號
輸入的批號不正確
示例 CoA
可下載CoA示例。注：該示例可能非最新批次的CoA。
目前沒有該產品的 CoA 示例。
分析圖譜
請輸入批號
輸入的批號不正確
很抱歉，您搜索的分析圖譜無法提供。