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CAS RN: 15421-84-8 | 產品號碼: T4243
| 產品號碼 | T4243 |
| 純度/分析方法 | >98.0%(HPLC)(qNMR) |
| 分子式 / 分子量 | C__1__0H__1__5N__5 = 205.27 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 15421-84-8 |
| Reaxys-RN | 186842 |
| MDL編號 | MFCD00193104 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 100.0 to 104.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 102 °C |
| 溶解性（微溶於） | Diethyl ether |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H301 : Toxic if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | XZ5700000 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2933.59-000 |
Application
Trapidil: A Platelet-Derived Growth Factor (PDGF) Antagonist
Trapidil was originally developed as an antiplatelet agent and vasodilator.1,2) Subsequently, trapidil has been reported as a platelet-derived growth factor (PDGF) antagonist with anti-proliferative effects.3,4) (The product is for research use only.)
References
- 1) Effect of trapidil on prostacyclin generation of arterial wall
- 2) Antithrombotic activity and the mechanism of action of trapidil (Rocornal®)
- 3) Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro
- 4) Trapidil Inhibits Platelet-Derived Growth Factor–Stimulated Mitogen-Activated Protein Kinase Cascade
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