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CAS RN: 52-49-3 | 產品號碼: T3303
Trihexyphenidyl Hydrochloride
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 247 °C(dec.) |
| 水溶性 | Slightly soluble |
| Degree of solubility in water | 10 g/l 25 °C |
| 溶解性（可溶於） | Alcohol, Chloroform |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | TN2625000 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
Trihexyphenidyl Hydrochloride: A M1 Muscarinic Cholinergic Receptor Antagonist
Trihexyphenidyl hydrochloride is a M1 muscarinic cholinergic receptor antagonist, and is used for the treatment of parkinsonian syndrome. The exact mechanism of action in parkinsonian syndromes is not precisely understood, but it is known that trihexyphenidyl has a direct anti-spasmodic effect on smooth muscles and a control effect on extrapyramidal disorders which may be caused by certain drugs acting on the central nervous system. (The product is for research purpose only.)
References
- Parkinsonism. Clinical and neuropharmacologic aspects
- Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine
- Comparative behavioral and neurochemical activities of cholinergic antagonists in rats
- Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats
考研文獻
TCIMail
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