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CAS RN: 491-67-8 | 產品號碼: T2721
| 產品號碼 | T2721 |
純度/分析方法 
|
>98.0%(T) |
| 分子式 / 分子量 | C__1__5H__1__0O__5 = 270.24 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 491-67-8 |
| Reaxys-RN | 272683 |
| PubChem Substance ID | 125307744 |
| Merck Index(14) | 942 |
| MDL編號 | MFCD00017459 |
產品規格
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 265 °C |
| 溶解性（可溶於） | Dimethylformamide |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
| RTECS # | DJ3100898 |
運輸資料
| HS編碼* | 2932.99-000 |
Application
Efflux pump research
Baicalein has been reported to inhibit TetK tetracycline efflux pump.1) The compound also showed synergy with tetracycline in a MRSA strain that doesn’t possess tetK, or with β-lactams.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Remarkable Synergies between Baicalein and Tetracycline, and Baicalein and β-Lactams against Methicillin-Resistant Staphylococcus aureus
- Baicalein Inhibits Staphylococcus aureus Biofilm Formation and the Quorum Sensing System In Vitro
- Virtual screening for novel quorum sensing inhibitors to eradicate biofilm formation of Pseudomonas aeruginosa
- Biological properties of baicalein in cardiovascular system (a review)
- New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin (a review)
- Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders (a review)
Application
Quorum sensing research / Biofilm research
References
Application
Baicalein: A Flavonoid with Various Pharmacological Activities Including Antioxidant and Anti-Tumor Activities
Baicalein is a flavonoid and one of the major constituent of the root of Scutellaria baicalensis, as well as wogonin [W0010] and baicalin [B2835]. Baicalein possesses a multitude of pharmacological activities. It has been reported that baicalein is a potent free radical scavenger and xanthine oxidase inhibitor, thus improving endothelial function and conferring cardiovascular protective actions against oxidative stress-induced cell injury. Furthermore, baicalein has potent anti- inflammatory and anti-tumor activities. Baicalein is cytotoxic to various human tumor cell lines in vitro and inhibit tumor growth in vivo. (The product is for research purpose only.)
References
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