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CAS RN: 26471-62-5 | 產品號碼: T0264
Tolylene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
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產品規格
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 98.0 %(total of isomer) |
性質
| 熔點 | 14 °C |
| 沸點 | 251 °C |
| flp | 137 °C |
| 比重 | 1.22 |
| 折射率 | 1.57 |
| 溶解性（可與之混溶） | Benzene, Acetone, Ether |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H330 : Fatal if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. H351 : Suspected of causing cancer. H412 : Harmful to aquatic life with long lasting effects. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相關法規
| RTECS # | NQ9490000 |
運輸資料
| UN編號 | UN2078 |
| 類別 | 6.1 |
| 包裝類別 | II |
| HS編碼* | 2929.10-100 |
Application
Reagent for airway hyperresponsiveness (asthma) model
References
- The development of an animal model for TDI asthma
- M. H. Karol, Bull. Eur. Physiopathol. Respir. 1987, 23, 571.
- An asthma model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate
- Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI)
- A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor
- Y. C. Lee, C. H. Song, H. B. Lee, J. L. Oh, Y. K. Rhee, H. S. Park, G. Y. Koh, J. Allergy Clin. Immunol. 2001, 108, 1021.
- Mesenchymal stem cell transfer suppresses airway remodeling in a toluene diisocyanate-induced murine asthma model
考研文獻
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