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CAS RN: 133865-89-1 | 產品號碼: S0935
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 8.70 to 9.70 % |
| Specific rotation [a]20/D | +15.0 to +19.0 deg(C=1, AcOH(95vol%)) |
| NMR | confirm to structure |
性質
| 熔點 | 212 °C |
| 比旋光 [α]D | 17° (C=1,95% CH3COOH) |
GHS
相關法規
| RTECS # | TX1457385 |
運輸資料
| HS編碼* | 2924.29-000 |
Application
Safinamide: A Na, K Channel Modulator and Monoamine Oxidase B (MAOB) Inhibitor
Safinamide is a sodium and calcium channel modulator, and also inhibits monoamine oxidase B (MAOB) which is an enzyme that catalyzes the oxidation of monoamines. Safinamide is used for the treatment of epilepsy and Parkinson's disease (PD). (The product is for research purpose only.)
References
- Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity
- Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs
- Safinamide (a review)
- Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions (a review)
- Safinamide in the treatment of Parkinson's disease (a review)
考研文獻
TCIMail
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