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CAS RN: 99755-59-6 | 產品號碼: R0220
| 產品號碼 | R0220 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__9H__2__5NOS = 315.48 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (<0°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器 | 10MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 99755-59-6 |
| Reaxys-RN | 5822772 |
| PubChem Substance ID | 468592791 |
| MDL編號 | MFCD00869590 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -34.0 ～ -38.0 deg(C=1, methanol) |
| NMR | confirm to structure |
性質
| 熔點 | 78 °C |
| 比旋光 [α]D | -42.7° (C=1,MeOH) |
| 水溶性 | Insoluble |
| Degree of solubility in water | 37.4 mg/l 25 °C |
| 溶解性（可溶於） | Ethanol, Dimethylformamide |
GHS
| 危險性說明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相關法規
| RTECS # | QK4252968 |
運輸資料
| HS編碼* | 2934.99-000 |
Application
Rotigotinei: A Non-Ergot Dopamine Receptor Agonist
Rotigotinei is a non-ergot dopamine receptor agonist. Rotigotinei is used as a curative medicine via a transdermal system for Parkinson's disease and restless legs syndrome. The precise mechanism of action of rotigotinei is unknown, although it is thought to be related to its ability to stimulate dopamine receptors. (The product is for research purpose only.)
References
- The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease
- Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors
- Rotigotine transdermal patch: a review of its use in the treatment of Parkinson's disease
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