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CAS RN: 53797-35-6 | 產品號碼: R0194
Ribostamycin Sulfate
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產品號碼 | R0194 |
純度/分析方法 | >90.0%(N) |
分子式 / 分子量 | C__1__7H__3__4N__4O__1__0·xH__2SO__4 |
外觀與形狀(20°C) | Solid |
儲存條件 | Refrigerated (0-10°C) |
應避免的情況 | Heat Sensitive |
包裝和容器 | 1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 53797-35-6 |
相關CAS RN | 25546-65-0 |
Reaxys-RN | 8820400 |
PubChem Substance ID | 354335294 |
Merck Index(14) | 8206 |
MDL編號 | MFCD00057496 |
產品規格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 97.0 area% |
Specific rotation [a]20/D | +41.0 to +45.0 deg(C=1,H2O) |
Drying loss | max. 5.0 % |
NMR | confirm to structure |
性質
熔點 | 180 °C |
比旋光 [α]D | 44° (C=1,H2O) |
GHS
圖形表示 |
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信號詞 | Danger |
危險性說明 | H360 : May damage fertility or the unborn child. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相關法規
運輸資料
HS編碼* | 2941.90-000 |
Application
Ribostamycin Sulfate: A Broad-Spectrum Aminoglycoside Antibiotic
Ribostamycin sulfate (SF-733) is a broad-spectrum aminoglycoside antibiotic isolated from Streptomyces ribosifidicus. It has activity against both Gram-negative and Gram-positive bacteria but has no activity against yeasts or fungi. Ribostamycin irreversibly binds to the 30S subunit (16S rRNA) of the bacterial ribosome as with any other aminoglycoside antibiotics, and then it inhibits bacterial growth by inhibiting protein synthesis. (The product is for research purpose only.)
References
- Antibiotic SF-733, a new antibiotic. I. Taxonomy, isolation, and characterization
- In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin, and fusidic acid against Borrelia burgdorferi
- Ribostamycin inhibits the chaperone activity of protein disulfide isomerase
- Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA
考研文獻
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