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CAS RN: 58-33-3 | 產品號碼: P2029
Promethazine Hydrochloride
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| 產品號碼 | P2029 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__7H__2__0N__2S·HCl = 320.88 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 應避免的情況 | Light Sensitive |
| CAS RN | 58-33-3 |
| 相關CAS RN
|
60-87-7 |
| Reaxys-RN | 4166397 |
| PubChem Substance ID | 160871508 |
| Merck Index(14) | 7786 |
| MDL編號 | MFCD00012652 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
性質
| 熔點 | 226 °C |
| Maximum Wavelength | 297 nm (H__2O) |
| 溶解性（不溶於） | Ether |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H411 : Toxic to aquatic life with long lasting effects. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | SO8225000 |
運輸資料
| UN編號 | UN3077 |
| 類別 | 9 |
| 包裝類別 | III |
| HS編碼* | 2934.30-000 |
Application
Efflux pump research / Biofilm research
References
- Antifungal activity of promethazine and chlorpromazine against planktonic cells and biofilms of Cryptococcus neoformans/Cryptococcus gattii complex species
- The Role of Efflux Pumps and Environmental pH in Bacterial Multidrug Resistance
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis
- In vitro effects of promethazine on cell morphology and structure and mitochondrial activity of azole-resistant Candida tropicalis
Application
Formulation and its Related Studies of Promethazine Hydrochloride
References
- Formulation of sustained-release promethazine hydrochloride tablets using hydroxypropyl methyl cellulose matrixes
- Adsorption of promethazine hydrochloride with KSF montmorillonite
- Release of cationic drugs from loaded clay minerals
- I. Fejer, M. Kata, I. Eros, O. Berkesi, I. Dekany, Colloid. Polym. Sci. 2001, 279, 1177.
- Colorimetric determination of captopril in dosage forms
- S. M. El-Ashry, F. A. Ibrahim, Anal. Lett. 1992, 25, 1657.
PubMed Literature
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