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CAS RN: 65-86-1 | 產品號碼: O0633
產品號碼 | O0633 |
純度/分析方法 | >95.0%(T)(HPLC) |
分子式 / 分子量 | C__5H__4N__2O__4 = 156.10 |
外觀與形狀(20°C) | Solid |
儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
儲存在惰性氣體下 | Store under inert gas |
應避免的情況 | Air Sensitive,Moisture Sensitive |
CAS RN | 65-86-1 |
Reaxys-RN | 383901 |
MDL編號 | MFCD00006027 |
產品規格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Purity(Neutralization titration) | min. 95.0 % |
NMR | confirm to structure |
性質
熔點 | 345 °C |
Degree of solubility in water | 1.82 g/l |
GHS
圖形表示 |
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信號詞 | Warning |
危險性說明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H335 : May cause respiratory irritation. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相關法規
RTECS # | RM3180000 |
運輸資料
HS編碼* | 2933.59-000 |
Application
Orotic Acid: An Essential Intermediate in the Biosynthesis of Pyrimidine Nucleotides
Orotic acid is known to be an essential intermediate in the biosynthesis of pyrimidine nucleotides. In mammals, it is released from mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to uridine monophosphate (UMP) by the cytoplasmic enzyme UMP synthase. Urinary orotic acid determination is a useful screening tool for many inborn errors of the urea cycle and a number of other disorders.
Reference
- Orotic acid, more than just an intermediate of pyrimidine de novo synthesis
- Orotate (orotic acid): An essential and versatile molecule
- Orotic acid excretion and arginine metabolism
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