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CAS RN: 113507-06-5 | 產品號碼: M3136
| 產品號碼 | M3136 |
純度/分析方法 
|
>98.0%(N) |
| 分子式 / 分子量 | C__3__7H__5__3NO__8 = 639.83 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Frozen (-20°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器
|
250MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 113507-06-5 |
| Reaxys-RN | 4649146 |
| PubChem Substance ID | 468592289 |
| Merck Index(14) | 6290 |
| MDL編號 | MFCD00866560 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 130.0 to 134.0 °C |
性質
| 熔點 | 132 °C |
| 比旋光 [α]D | 140° (C=1,CHCl3) |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H301 : Toxic if swallowed. H410 : Very toxic to aquatic life with long lasting effects. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P391 : Collect spillage. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | PY5438800 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2932.99-000 |
Application
Moxidectin: A Macrocyclic Lactone with Anthelmintic Activity
Moxidectin, a macrocyclic lactone, is an anthelmintic and a semisynthetic methoxime derivative of naturally occurring nemadectin. It is well known for the action against a broad range of animalparasites. The precise mechanism of action is unknown, but studies with nematodes suggest that moxidectin binds to glutamate-gated chloride channels (GluCl), gamma-aminobutyric acid (GABA) receptors and/or ATP-binding cassette (ABC) transporters, causing muscle paralysis and death of the parasite. (The product is for research purpose only.)
References
- Moxidectin: a review of chemistry, pharmacokinetics and use in horses (a review)
- Macrocyclic lactones in the treatment and control of parasitism in small companion animals (a review)
- Analysis of avermectin and moxidectin residues in milk by liquid chromatography-tandem mass spectrometry using an atmospheric pressure chemical ionization/atmospheric pressure photoionization source
- Determination of anthelmintic drug residues in milk using ultra high performance liquid chromatography-tandem mass spectrometry with rapid polarity switching
- Analytical profile of moxidectin (a review)
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